Figure 3. miR-122-5p targeted at SDC1_3′UTR and downregulated SDC1 expression.

(A) Overexpression of miR-122-5p inhibited SDC1 protein expression. (B) Luciferase reporter assay showed direct targeting of miR-122-5p at SDC1_3′UTR. Mutation at miRNA-binding sites at 3′UTR abolished inhibitory effect. Data were mean ± S.E. ^**p < 0.01, ^*p < 0.05.