Figure 3.

Quantification and qualification of damage in the brain of infected mice. Groups of BALB/c mice (n = 4 each), mock, 2^nd and 7^th d.p.i. were considered for quantification and qualification of damage in their brains. Three types of tissue damage were taken into account: (i) hemorrhage; (ii) perivascular infiltrate; and (iii) pia mater infiltrate. 30 fields of HE-stained histological cuts at magnification of 400× were evaluated according to an arbitrary scale as follows: 0 - absent; 1 - light and focal; 2 - light; 3 - moderate; and 4 - diffuse. Raw data is available in the Supplementary Information, Table 1. d.p.i. - days post infection; ID - identification number of animal.