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. 2018 Jun 27;8:9754. doi: 10.1038/s41598-018-28137-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Ultrastructural aspects of the cerebellum tissue of BALB/c mice infected with DENV-2. (A) Pyramidal neurons, (C) microglial cells and (D) organized myelin fibers in samples from non-infected mice. Samples from infected mice showing (B) Purkinje neuron with increased nucleus and swollen mitochondria, (D) microglial cell with swollen mitochondria and (F) disorganized myelin fibers. Samples from infected mice were considered on the 7^th d.p.i. M - mitochondria; MF - myelin fibers; N - nucleus; d.p.i. - days post infection.