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. 2018 Jun 21;9:1414. doi: 10.3389/fimmu.2018.01414

Figure 4.

Figure 4

Interferon-γ signaling in cutaneous and uveal melanoma (UVM). (A) Expression of mRNA transcripts for IRF1, STAT1, and STAT3 in the 80 uveal [The Cancer Genome Atlas (TCGA) UVM dataset] and 472 cutaneous melanoma samples (TCGA skin cutaneous melanoma dataset). (B) Single sample gene set enrichment analysis (ssGSEA) scores for the Hallmark_interferon_alpha and Hallmark_interferon_gamma response signatures in the 80 uveal and 472 cutaneous melanoma samples from the TCGA datasets. Expression levels were compared using a nonparametric Mann–Whitney test, p values are indicated.