Table 1.
Interaction of different miRNAs with AQPs in several pathophysiological conditions.
| Gene | miRNA | Tissue | Disease/condition | References |
|---|---|---|---|---|
| AQP1 | 29a | Colon | IBS | Chao et al., 2017 |
| 126-5p | Lung | Acute lung injury | Tang et al., 2016 | |
| 144-3p | Lung | Acute lung injury | Li et al., 2018 | |
| 320a | Brain | Cerebral ischemia | Sepramaniam et al., 2010 | |
| Spinal cord | Spinal cord edema | Li et al., 2016 | ||
| 320 | Breast | Breast cancer | Luo et al., 2018 | |
| 666 | Liver | Cirrhosis | Huebert et al., 2011 | |
| 708 | Liver | Cirrhosis | Huebert et al., 2011 | |
| AQP2 | 32 | Kidney | Water reabsorption | Kim et al., 2015 |
| 137 | Kidney | Water reabsorption | Kim et al., 2015; Ranieri et al., 2018 | |
| AQP3 | 1 | Epidermis | Wound healing | Banerjee and Sen, 2015 |
| 29a | Colon | IBS | Chao et al., 2017 | |
| 124 | Liver | HCC | Chen et al., 2018 | |
| 185-5p | Epidermis | SCC | Ratovitski, 2013 | |
| 874 | Stomach | GC | Jiang et al., 2014 | |
| Intestine | Intestinal ischemic injury | Zhi et al., 2014 | ||
| Pancreas | PDAC | Huang et al., 2017 | ||
| AQP4 | 19a | Brain | Astrocyte connectivity | Jullienne et al., 2018 |
| 29b | Brain | Cerebral ischemia | Wang et al., 2015 | |
| 130a | Brain | Cerebral ischemia | Sepramaniam et al., 2012 | |
| Brain | AD | Zhang et al., 2017 | ||
| 130b | Brain | Cerebral ischemia | Zheng et al., 2017b | |
| 145 | Brain | Cerebral ischemia | Zheng et al., 2017a | |
| 203 | Lung | Asthma | Jardim et al., 2012 | |
| 224 | Brain | Astrocyte connectivity | Jullienne et al., 2018 | |
| 320a | Brain | Cerebral ischemia | Sepramaniam et al., 2010 | |
| Brain | Epilepsy | Song et al., 2015 | ||
| Brain | Glioma | Xiong et al., 2018 | ||
| AQP5 | 21 | Gallbladder | Gallbladder carcinoma | Sekine et al., 2013 |
| 96 | Lung | Sepsis | Zhang et al., 2014; Rump and Adamzik, 2018 | |
| 330 | Lung | Sepsis | Zhang et al., 2014; Rump and Adamzik, 2018 | |
| AQP8 | 16 | Colon | Ulcerative colitis | Min et al., 2013 |
| 29a | Colon | IBS | Chao et al., 2017 | |
| 195 | Colon | Ulcerative colitis | Min et al., 2013 | |
| 330 | Colon | Ulcerative colitis | Min et al., 2013 | |
| 424 | Colon | Ulcerative colitis | Min et al., 2013 | |
| 612 | Colon | Ulcerative colitis | Min et al., 2013 | |
| AQP9 | 22 | Liver | Diabetes | Karolina et al., 2014 |
| 23a | Liver | Diabetes | Karolina et al., 2014 |
AD, Alzheimer's disease; HCC, hepatocellular carcinoma; IBS, irritable bowel syndrome; GC, gastric cancer; PDAC, pancreatic ductal adenocarcinoma; SCC, squamous cell carcinoma.