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. 2018 Jun 21;9:765. doi: 10.3389/fphys.2018.00765

FIGURE 1.

FIGURE 1

Src inhibitor PP2 attenuated AGE-enhanced HUVECs proliferation, migration, and tube formation. HUVECs were incubated with 15 μmol/L PP2 for 90 min and then exposed to 100 μg/mL AGEs for 24 h. CCK-8 was used to evaluate the proliferation of HUVECs (A). Scratch wound healing (B) and transwell migration assay (C) were used to measure the migration of HUVECs. The tube length, numbers of branch points, and vessel area were observed in Matrigel medium (D). n ≥ 4 independent experiments. ∗P < 0.05 versus control, #P < 0.05 versus AGEs.