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Impact of brilliant blue (BBG) and probenecid on shock-induced protein expression. Contused rats exhibited increased expression of TNF (A), caspase-3 (C), and caspase-8 (E) 3 h after they were exposed to shock. BBG attenuated shock-induced caspase-1 (B) and IL-1ß (D) expression, whereas probenecid generally increased expression. Shock treatment increased IL-18 (F) expression. Error bars indicate the SEM (n = 6). *p < 0.05.
