Table 1.
Population baseline characteristics—The Memento cohort
| Characteristics | All participants (N = 2157) | FDG-PET participants (n = 1310) | FDG-PET performed yes versus no (P-value) |
|---|---|---|---|
| Median age in years, (Q1; Q3) | 71.6 (65.6; 77.1) | 72 (65.8; 77.0) | .55 |
| Female gender, n (%) | 1335 (61.9) | 770 (58.8) | .0002 |
| Educational level > 12 years, n (%) | 1172 (54.5) | 732 (56.0) | .070 |
| Number of APOE ε4 allele, n (%) | .99 | ||
| 0 | 1445 (70.4) | 890 (70.4) | |
| 1 | 537 (26.2) | 332 (26.2) | |
| 2 | 70 (3.4) | 43 (3.4) | |
| CDR score, n (%) | .018 | ||
| 0 | 869 (40.3) | 554 (42.3) | |
| 0.5 | 1288 (59.7) | 756 (57.7) | |
| Cognitive status, n (%) | .045 | ||
| SCD | 343 (15.9) | 219 (16.7) | |
| Pure aMCI | 196 (9.1) | 112 (8.5) | |
| Multi-domain aMCI | 924 (42.8) | 533 (40.7) | |
| Pure naMCI | 366 (17.0) | 237 (18.1) | |
| Multi-domain naMCI | 328 (15.2) | 209 (16.0) | |
| Median MMSE score, (Q1; Q3) | 28 (27; 29) | 28 (27; 29) | |
| FCSRT scores, median (Q1; Q3) | |||
| IR (/16) | 16 (15; 16) | 16 (15; 16) | .97 |
| FR (/48) | 27 (21; 32) | 27 (21; 32) | .078 |
| ISC (/100) | 89 (77; 96) | 89 (77; 96) | .25 |
Abbreviations: CDR, clinical dementia rating; MMSE, Mini Mental State Evaluation; FCSRT, Free and Cued Selective Reminding Test; IR, immediate recall; FR, free recall; ISC, index of sensitivity to cueing; SCD, subjective cognitive decline; aMCI, amnestic mild cognitive impairment; naMCI, nonamnestic mild cognitive impairment; FDG-PET, fluorodeoxyglucose-positron emission tomography.
NOTE. Between-group comparisons were performed through χ2 test for discrete variables or analysis of variance tests for continuous variables.