Table 1.

Reported advantages and disadvantages of knowing amyloid PET result

Advantages/benefits

Disadvantages/risks

-The opportunity of receiving the result in an early stage of the disease course. -The ability to inform others -The ability to enjoy life more consciously -The ability to make lifestyle changes (healthier lifestyle) -Knowledge about the underlying cause of the memory problems -The possibility to participate in AD drug trials - The ability to make arrangements for the future, such as ○ Financial arrangements ○ Legal arrangements ○ Life insurance ○ Advance directives ▪Future care and treatment options ▪Arranging elderly care or residential care center ▪ Depending on legislation: euthanasia request ○ Household tasks ○ Move to a smaller place/house

-Emotional risk of knowing the result -The lack of an effective disease-modifying treatment -Risks of undergoing tests -Trial participation is time-consuming -The possibility of an equivocal test result -The cost of tests -The fear of future cognitive decline -Negative stigma/label -The possibility of being patronized by others, such as by relatives and friends.

NOTE. Table 1 is based on the advantages and disadvantages as reported in the following studies [12]^, [14]^, [15]^, [16]^, [22]^, [23]^, [24]^, [25]^, [26]^, [27].

Abbreviation: AD, Alzheimer's disease.