Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PK model parameters
| Parameter | Description |
|---|---|
| D | Oral dose |
| Fmax | Maximum bioavailability |
| ED50 | Bioavailability oral dose at half-maximum effect |
| βF | Bioavailability fed-state coefficient |
| τF | Bioavailability time constant |
| ka | Oral absorption rate constant |
| BW | Scaled body wt |
| VC | Volume of distribution allometric constant |
| CLC | Clearance allometric constant |
