TABLE 1.
Data collection statistics for APH(2″)-Ia and APH(2″)-Ia S376N data setsa
| Parameter | Value or description |
|||||
|---|---|---|---|---|---|---|
| WT APH-GMPPNP-ribostamycin (alternate) | WT APH-GMPPNP- lividomycin | WT APH-GMPPNP- dibekacin | WT APH-GMPPNP- amikacin | WT APH-GMPPNP- arbekacin | APH-S376N-GMPPNP | |
| PDB ID | 6C5U | 6CEY | 6CAV | 6CGD | 6CGG | 6CH4 |
| Data collection statistics | ||||||
| Space group | P21 | P21 | P21 | P21 | P21 | P21 |
| a, b, c (Å) | 90.2, 100.3, 94.0 | 90.2, 100.2, 94.0 | 89.9, 98.3, 93.2 | 90.1, 100.2, 94.0 | 90.3, 99.8, 93.5 | 90.4, 99.9, 93.2 |
| α, β, γ (°) | 90, 105.3, 90 | 90, 105.2, 90 | 90, 105.2, 90 | 90, 105.1, 90 | 90, 105.4, 90 | 90, 105.2, 90 |
| Resolution (Å) | 90.71–2.42 (2.48–2.42) | 59.07–2.40 (2.46–2.40) | 98.34–2.60 (2.68–2.60) | 50.11–2.20 (2.24–2.20) | 99.78–2.40 (2.46–2.40) | 58.89–2.30 (2.35–2.30) |
| CC1/2 | 0.998 (0.173) | 0.988 (0.287) | 0.978 (0.358) | 0.991 (0.557) | 0.992 (0.383) | 0.987 (0.434) |
| Rmerge | 0.079 (1.543) | 0.110 (1.345) | 0.162 (1.072) | 0.115 (1.022) | 0.115 (1.024) | 0.133 (0.965) |
| I/σI | 8.5 (1.0) | 10.0 (1.8) | 4.7 (1.2) | 10.5 (1.8) | 6.1 (1.0) | 9.7 (1.9) |
| Completeness (%) | 100.0 (99.8) | 100.0 (100.0) | 100.0 (99.8) | 100.0 (100.0) | 100.0 (100.0) | 100.0 (100.0) |
| Multiplicity | 3.8 (3.6) | 4.2 (4.2) | 3.7 (3.5) | 4.3 (4.3) | 3.8 (3.7) | 4.3 (4.3) |
a
WT, wild type; CC1/2, half-dataset correlation coefficient.