FIG 4.

LC-MS EICs of SKLB-TB1001 metabolites for the synthesized standard and in mouse plasma. (a) LC-MS EIC of M3 of the synthesized standard (retention time [RT] = 3.73 min) and in mouse plasma (RT = 3.85 min); (b) LC-MS EIC of M4 for the synthesized standard (RT = 4.02 min) and in mouse plasma (RT = 4.10 min); (c) LC-MS EIC of M6 for the synthesized standard (RT = 4.67 min) and in mouse plasma (RT = 4.69 min); (d) LC-MS EIC of M7 for the synthesized standard (RT = 4.82 min) and in mouse plasma (RT = 4.86 min).