TABLE 3.

PK parameters of M7 after a 5-mg/kg i.v. or p.o. dose of SKLB-TB1001 in male SD rats

PK parameter	U	Value		SD		CV (%)
		i.v.	p.o.	i.v.	p.o.	i.v.	p.o.
Tmax	h	0.417	0.50	0.144	0.00	34.6	0.00
Cmax	ng/ml	70.6	17.9	25.0	13.5	35.4	75.2
AUClast	h · ng/ml	163	62.8	21.3	46.8	13.1	74.6
AUCINF	h · ng/ml	167	94.0	21.2	NA	12.7	NA
Terminal t1/2	h	1.53	1.84	0.108	NA	7.05	NA