FIG 5.
In vitro activity of C31 against three flaviviruses. Shown are dose-dependent curves of antiviral activity against DENV, ZIKV, and YFV. Viral replication was assessed by RT-qPCR at 48 h postinfection. Relative replication was expressed as a percentage of the value for the untreated control and plotted against the log10 concentration of C31. The EC50s are shown on the graph and are represented by a dashed line. Data shown are means ± SD of results from at least two independent experiments performed in triplicate.