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Adverse effects associated with amikacin inhalation-containing regimens
| Adverse effect | No. (%) of patients with: |
||
|---|---|---|---|
| Discontinuation | Regimen changea | Total | |
| Total | 21 (27) | 8 (10) | 29 (38) |
| Ototoxicity | 11 (14) | 4 (6) | 15 (19) |
| Fatigue | 6 (8) | 1 (1) | 7 (9) |
| Tinnitus | 3 (4) | 1 (1) | 4 (5) |
| Cough | 1 (1) | 1 (1) | 2 (3) |
| Hoarseness | 0 | 1 (1) | 1 (1) |
| Nephrotoxicity | 0 | 0 | 0 |
Change of amikacin inhalation from 500 mg once daily to 500 mg three times weekly.
