Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 2;30(3-4):163–177. doi: 10.1080/01677063.2016.1229781

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/Licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — The voltage-gated sodium channel as a target for pyrethroids. (a) Diagram of the voltage gated sodium channel showing the four repeat domains (I-IV), each comprising six membrane spanning helices (S1-S6). The positions of resistance mutations that identify pyrethroid binding sites PyR1 (red circles) and PyR2 (blue circles) are highlighted. The proposed PyR1 (b) and PyR2 (c) sites are shown in more detail, taken from O'Reilly et al. (2006) and Du et al. (2013). Positions of the mutations originally identified in pyrethroid and DDT-resistant para^ts Drosophila strains are also shown (yellow circles).