Table 2. Behavior of mice and CV of parameter in open field and elevated plus maze tests.
| Behavior | SAL | DZ | |||
|---|---|---|---|---|---|
| Tunnel | Tail | Tunnel | Tail | ||
| OFT | |||||
| Line crossing (n) | 496.5 ± 107.7a) | 400.45 ± 96.3a) | 471.25 ± 150.3 | 376.8 ± 230.0 | |
| 21.69 | 24.04 | 31.90 | 61.05 | ||
| Time in inner area (%) | 20.57 ± 8.0a) | 14.35 ± 6.8a) | 15.07 ± 7.8 | 13.1 ± 9.2 | |
| 39.03 | 47.42 | 52.02 | 70.00 | ||
| EPM | |||||
| Total entry (n) | 28.1 ± 4.6a) | 21.8 ± 7.9a) | 30.2 ± 13.9 | 22.25 ± 13.3 | |
| 16.30 | 36.25 | 45.95 | 59.79 | ||
| Open arm entry (n) | 12.25 ± 3.0a,b) | 10.7 ± 5.0a) | 19.9 ± 8.5b) | 15.65 ± 8.6 | |
| 24.88 | 46.65 | 42.87 | 55.16 | ||
| Time on open arms (%) | 33.67 ± 9.8a,b) | 39.15 ± 13.0a,b) | 69.78 ± 20.6b) | 73.22 ± 15.0b) | |
| 28.99 | 33.30 | 29.58 | 20.49 | ||
Values showed the means ± SD. n=20 animals per group. a) P<0.05 tunnel vs tail, b) P<0.05 SAL vs DZ comparison tunnel handled. SAL, saline; DZ, diazepam; OFT, open field test; EPM, elevated plus maze.