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. 2018 Jan 15;10(3):283–296. doi: 10.4155/fmc-2017-0159

Table 1. . Antibacterial activities of compounds against staphylococcal strains.

Strains Antibacterial activity of compounds (MIC, μg/ml)

Name Type OZE-I OZE-II OZE-III Vancomycin Oxacillin
Newman MSSA 16 16 32 2 ≤0.0625

MW2 MRSA 8 8 16 4 64

ATCC 29213 MSSA 8 8 16 2 0.5

ATCC 33591 MRSA 4 4 16 2 >64

USA100 MSSA 4 8 16 2 ≤0.0625

USA300 MRSA 4 4 8 4 >64

USA400 MRSA 8 8 16 2 >64

MIC: Minimum inhibitory concentration; MRSA: Methicillin-resistant Staphylococcus aureus; MSSA: Methicillin-susceptible S. aureus; OZE-I: N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl) cyclopropanecarboxamide; OZE-II: N-(5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-((4,4-dimethyloxazolidin-3-yl) sulfonyl) benzamide; OZE-III: N-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl) pentanamide.