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. 2018 Feb 22;10(5):643–659. doi: 10.2217/epi-2017-0105

Figure 5. . Differential Methylation CpG loci analysis results in ROSMAP dataset.

Figure 5. 

(A) The Venn diagram plot of the differentially methylated CpG loci obtained from differently processed data. The datasets including B(C): data corrected for the batch effect), and PB(C): data corrected for the positional and batch effect sequentially by ComBat. (B) The sample distribution in cognitive diagnostic of ROSMAP data in 12 positions. The values showed in the figure are the control and dementia samples percentages in position four and five. Venn diagram showing the number of differentially methylated CpGs (false discovery rate <0.05) between each pair of datasets.