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. 2018 Feb 5;19(5):413–434. doi: 10.2217/pgs-2017-0186

Figure 3. . Lithium pharmacogenomics gene Gene Set Enrichment Analysis results.

Figure 3. 

(A) Top diseases and functions detected by IPA® for ten genes detected in the original lithium experiment. (B) Top diseases and functions for the 12 genes detected in the PIP lithium experiment. Although there is significant overlap in the top nine hits for the two gene sets (five categories) there are some significant differences, demonstrating that the extra discerning power of the automated methods may be adding value relative to the semi-manual experiments.

IPA®: Ingenuity® Pathway Analysis; PIP: Pharmacoepigenomics informatics pipeline.