Table 4.
Typical progresses of inertial microfluidics integrated with other technologies.
| Category | Target | Characteristic | Optimum Performance | Reference |
|---|---|---|---|---|
| Inertial Microfluidics & Magnetophoresis | CTCs | a device integrated deterministic lateral displacement, inertial focusing and magnetophoresis | •Processing rate: 8 mL whole blood/h •Throughput: 107 cells/s •Recovery: 97% |
[108] |
| cancer cell & microbeads | the integration of a micromixer unit and an inertial flow unit for the detection and separation | •Binding efficiency:97.1% | [105] | |
| CTCs | a microvortex-generating herringbone-chip | •Processing cell density: 386 ± 238 CTCs/mL •Capture efficiency: 91.8 ± 5.2% |
[116] | |
| Inertial Microfluidics & Dielectric | mRNAs in single living cells | a filter region and a serpentine-shape single-cell trapping channel | •An average single-cell occupancy of 94 ± 4% •Flow rate: 2 μL/min |
[110] |
| Inertial Microfluidics & Acoustic | CTCs | taSSAW-based high-throughput cell separation device | •Recovery: 83% •Removal rate of WBCs: ∼90% •Throughput: 1.2 mL/h |
[113] |
| fluorescent particle | a conductive liquid-based focused surface acoustic wave (CL-FSAW) device | •Mixing efficiency: higher than 90% •Flow rate:120 μL/min •Mixing time of the CL-FSAW device: 20 ms |
[120] | |
| bacteria in blood | a main channel of rectangular cross-section and symmetric trifurcating inlets/outlets | •RBCs remove: more than 85% •Yield of spiked bacteria: 40–60% |
[49] |