Table 1. . Details of the participants from the five cohorts whose data were used in this study.
| Participant characteristics | BREATHE n = 1459 | PACMAN n = 996 | PAGES n = 970 | GALA II n = 1330 | BAMSE n = 165 | |
|---|---|---|---|---|---|---|
| Male sex, % (n) | 60% (592) | 64% (458) | 59% (284) | 58% (772) | 60.6% (100) | |
| Mean age in years (SD) | 9.6 (3.8) | 8.4 (2.4) | 9.5 (3.8) | 11.9 (2.7) | 8.3 (0.45) | |
| Exposed to second hand smoke at home, % (n) | 36% (337) | 10% (69) | 23% (107) | 21% (283) | 21.8% (36) | |
| With recent attack, % (n) | 44% (430) | 9% (59) | 60% (261) | 66% (884) | 10% (17) | |
| GSTM1 status | Active type (%) | 52% (508) | 49% (351) | 45% (223) | NA | NA |
| Null (%) | 48% (475) | 51% (368) | 55% (272) | NA | NA | |
| GSTT1 status | Active type (%) | 79% (777) | 78% (564) | 79% (393) | NA | NA |
| Null (%) | 21% (206) | 22% (155) | 21% (102) | NA | NA | |
| GSTP1 status | Ile/Ile | 40% (395) | 40% (287) | 45% (222) | 34% (453) | 46% (76) |
| Ile/Val | 47% (459) | 46% (329) | 42% (209) | 46% (615) | 47% (77) | |
| Val/Val | 13% (129) | 14% (103) | 13% (64) | 20% (262) | 7% (12) | |
| Number of GST mutants | 0 | 34% (331) | 33% (240) | 33% (163) | NA | NA |
| 1 | 51% (504) | 48% (346) | 47% (232) | NA | NA | |
| 2 | 14% (138) | 17% (119) | 19% (94) | NA | NA | |
| 3 | 1% (10) | 2% (14) | 1% (6) | NA | NA | |
| BTS/SIGN treatment step | No treatment or 1 | 15% (147/945) | 14% (93/674) | 8% (35/456) | 49% (649/1330) | 40%(66) |
| 2 | 55% (523/945) | 62% (418/674) | 25% (115/456) | 21% (283/1330) | 59.3%(98) | |
| 3 | 16% (147/945) | |||||
| 18% (123/674) | 55% (251/456) | 9% (123/1330) | 0.7% (1) | |||
| 4 or 5 | 14% (128/945) | 6% (40/674) | 12% (55/456) | 21% (275/1330) | 0 | |
NA: Not available.