Algorithm 2 Pseudo-code of seizure prediction framework

1: procedure Prediction($S_{\mathrm{ecog}}$, $PA$) 2:         input: $S_{\mathrm{ecog}}$ 3:         output: $PA$ (prediction alarm) 4:         repeat 5:                 for every 20 s window of $S_{\mathrm{ecog}}$ do 6:                      $\mathcal{X}$ = Extract feature($S_{\mathrm{ecog}}$) 7:                      $(\mathcal{Y},\mathcal{V},\mathcal{U})$ = Classify$\left(\mathcal{X}\right)$ 8:                 end for 9:                 while !(time == 60 mins) do 10:                      $\widehat{\mathcal{Y}}$ = $\mathcal{Y}$ (accumulate the labels for 1 h) 11:                 end while 12:                 if !(Threshold($\widehat{\mathcal{Y}}$)) then 13:                      $\mathcal{A}$ = Active Learner($\mathcal{X},\mathcal{U},\widehat{\mathcal{Y}},\mathcal{V}$) 14:                      $\mathcal{Y}=\mathtt{expert}\left\{\mathcal{A}\right\}$ (Obtain labels) 15:                      update $\theta \left(\mathcal{X}\right)$(Update base classifier model) 16:                 else 17:                      return $PA$ 18:                 end if 19:         until End of $S_{\mathrm{ecog}}$ 20: end procedure