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. 2018 Jun 20;8:186. doi: 10.3389/fcimb.2018.00186

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Copyright © 2018 Ayana, Yadav, Kumari, Ramu, Garg, Pati and Singh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Effects on flagellar beating upon inhibition of palmitoylation. (i) Time-lapse video microscopy showed detrimental effects on flagellar motility upon treatment with 2-BMP inhibitor. The scale indicates 5 μm. (ii) The graph shows linear, attenuated waveform for 2-BMP treated flagella, while untreated flagella displayed healthy beating with unattenuated waveforms. (B) Quantitative estimation of amastigote counts per 100 macrophages following 2-BMP treatment was used for evaluating host invasion efficiency (**p < < 0.05). Data are represented as mean ± SEM.