Scheme 3.
Synthesis of target compounds 11a–d and 13a, b; Reagents and conditions: (i) EtOH/AcOH(catalytic)/reflux 6h (ii) Dioxane/TEA (catalytic)/reflux 8h.
Synthesis of target compounds 11a–d and 13a, b; Reagents and conditions: (i) EtOH/AcOH(catalytic)/reflux 6h (ii) Dioxane/TEA (catalytic)/reflux 8h.