(b) Simultaneous targeting of LNL and FNFL cassettes
| Clones with LNL heteroinsertion | Clones with LNL homoinsertion | Clones with FNFL heteroinsertion | Clones with FNFL homoinsertion | Clones with simultaneous LNL and FNFL homoinsertion | ||
|---|---|---|---|---|---|---|
| 10 kb promoter | Number of clones Total clone number :432 |
194 | 16 | 165 | 24 | 1 |
| Efficiency | 44.9% | 3.7% | 38.2% | 5.5% | 0.2% |