Table 1.
Characteristics | n (%) |
---|---|
Age at initial treatment, years; median (range) | 59 (45–66) |
Gender | |
Female | 1 (4) |
Male | 22 (96) |
Disease stage at diagnosis | |
I | 0 (0) |
II | 2 (9) |
III | 4 (17) |
IV | 16 (70) |
Unknown | 1 (4) |
Extranodal disease at diagnosis | |
No | 7 (30) |
Yes | 16 (70) |
Time from auto-HCT to initial maintenance treatment (months); median (range) | 3.5 (2.3–5.8) |
MIPI at diagnosis | |
Low | 10 |
Intermediate | 12 |
High | 0 |
Unknown | 1 |
Conditioning regimens for prior auto-HCT | |
BEAM | 18 (78) |
CBV | 5 (22) |
Induction regimens | |
R-bendamustine | 3 |
R-HCVAD/MTX/ARA-C | 8 |
NORDIC | 4 |
RCHOP | 3 |
VR-CAP | 2 |
Ibrutinib | 1 |
Relapsed | |
RCHOP followed by R-HCVAD/MTX/ARA-C | 1 |
RCHOP followed by R-bendamustine | 1 |
Abbreviations: BEAM carmustine, cytarabine, etoposide, and melphalan; CBV cyclophosphamide, carmustine, and etoposide; R, rituximab; MTX methotrexate; Ara-C cytarabine; NORDIC maximum-strength rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone alternating with rituximab, high-dose cytarabine; R-HCVAD rituximab, cyclophosphamide, vincristine, doxorubicin, dexamethasone; RCHOP rituximab, cyclophosphamide, doxorubicin vincristine, and prednisone; VR-CAP bortezomib, rituximab, cyclophosphamide, doxorubicin, prednisone