Table 2.
Treatment-related adverse events
| Category | Toxicity | Number of patients (%) | ||
|---|---|---|---|---|
| Grade 2 | Grade 3 | Grade 4 | ||
| Blood/bone marrow | Leukocyte count decreased | 3 (13) | 10 (43) | |
| Lymphocyte count decreased | 7 (30) | 1 (4) | ||
| Neutrophil count decreased | 1 (4) | 7 (30) | 10 (43) | |
| Platelet count decreased | 3 (13) | 1 (4) | ||
| Cardiac general | Hypertension | 5 (22) | 1 (4) | |
| Constitutional symptoms | Chills | 1 (4) | ||
| Fatigue | 3 (13) | |||
| Fever | 1 (4) | |||
| Infection | Skin infection | 1 (4) | 1 (4) | |
| Wound infection | 1 (4) | |||
| Lung infection | 1 (4) | 2 (9) | ||
| Musculoskeletal/soft tissue | Arthralgia | 1 (4) | ||
| Neurology | Peripheral sensory neuropathy | 2 (9) | ||
| Skin | Rash | 1 (4) | ||