Table 2.
Biological function of soluble factor secreted by MSCs.
| Soluble factors | Biological function |
|---|---|
| IDO | Suppressing proliferation and effect of immune cells |
| TSG6 | Anti-inflammatory effect |
| NO | Suppressing proliferation and modulation of T cell, promoting apoptosis of immune cells |
| IL-10 | Suppressing apoptosis of immune cells |
| CCL2 | Suppressing activation and migration of TH17 cells, promoting migration of monocyte |
| PGE2 | Suppressing generation and migration of TNF, proliferation of T cell, and cytolytic activity of NK cell |