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. 2018 Jun 14;2018:3057624. doi: 10.1155/2018/3057624

Table 2.

Biological function of soluble factor secreted by MSCs.

Soluble factors Biological function
IDO Suppressing proliferation and effect of immune cells
TSG6 Anti-inflammatory effect
NO Suppressing proliferation and modulation of T cell, promoting apoptosis of immune cells
IL-10 Suppressing apoptosis of immune cells
CCL2 Suppressing activation and migration of TH17 cells, promoting migration of monocyte
PGE2 Suppressing generation and migration of TNF, proliferation of T cell, and cytolytic activity of NK cell