Table 1.
Clinical characteristics and body composition (median, IQR)
| Variable | Men (n = 94) | Women (n = 114) | p |
|---|---|---|---|
| Clinical characteristics | |||
| Age (years) | 34.5, 28.8–42.0 | 38.0, 29.8–43.3 | 0.2 |
| Height (cm) | 177, 173–183 | 163, 158–168 | < 0.0001 |
| Weight (kg) | 105, 96–124 | 91, 78–101 | < 0.0001 |
| Body mass index (kg/m2) | 34, 31–39 | 34, 29–38 | 0.4 |
| DXA parameters | |||
| Total fat mass (kg) | 34, 29–48 | 38, 31–47 | 0.4# |
| Total fat mass (%) | 33.4, 28.5–37.5 | 42.2, 38.3–45.9 | < 0.0001*# |
| Lower extremity fat (kg) | 12, 10–16 | 14, 11–18 | 0.001*# |
| Lower extremity fat/total fat | 0.38, 0.35–0.42 | 0.33, 0.30–0.36 | < 0.0001*# |
| Appendicular lean mass (kg) | 33, 29–37 | 23, 20–25 | < 0.0001*# |
| Appendicular lean mass/weight | 0.30, 0.28–0.33 | 0.25, 0.23–0.27 | < 0.0001*# |
| CT parameters | |||
| Abdominal SAT (cm2) | 386, 292–560 | 455, 325–567 | 0.07*# |
| Visceral adipose tissue (VAT) (cm2) | 149, 122–208 | 106, 69–139 | < 0.0001*# |
| VAT/SAT | 0.36, 0.25–0.54 | 0.23, 0.17–0.33 | < 0.0001*# |
| Thigh SAT (cm2) | 128, 94–148 | 171, 136–233 | < 0.0001*# |
| Thigh muscle (cm2) | 198, 177–219 | 141, 124–153 | < 0.0001*# |
| 1H-MRS parameters | |||
| Intrahepatic lipids (lipid/water) | 0.06, 0.03–0.17 | 0.05, 0.02–0.13 | 0.1*# |
| Soleus intramyocellular lipids (lipid/water) | 0.04, 0.02–0.05 | 0.03, 0.02–0.04 | 0.0005*# |
Abbreviations: DXA dual energy x-ray absorptiometry, CT computed tomography, SAT subcutaneous adipose tissue, 1H-MRS proton magnetic resonance spectroscopy
*Significant after controlling for age
#Significant after controlling for BMI