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. 2018 Jun 14;2018:3096183. doi: 10.1155/2018/3096183

Figure 2.

Figure 2

Defective function of Treg cells in immune-suppression. (a) Representative examples of flow cytometry analysis of Nrp-1, CTLA-4, and GITR expression by CD4+CD25+ Treg cells in healthy and asthmatic subjects. (b, c, d) Frequencies of Nrp-1 CTLA-4 and GITR expressed in healthy and asthmatic subjects. (e) Representative examples of flow cytometry analysis of IL-10 and TGF-beta production by CD4+CD25+ Treg cells in healthy and asthmatic subjects. (f, g) Frequencies of IL-10 and TGF-beta production in healthy and asthmatic subjects. The graph shows means ± sem. ∗∗p < 0.01 and ∗∗∗∗p < 0.0001. NS: no significance.