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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Environ Int. 2017 Apr 6;104:102–109. doi: 10.1016/j.envint.2017.03.019

Table 3.

Mediation Analysis: Mediators of the Association Between PM2.5 and Cognitive Functiona

Mediators
Depression Anxiety Stress CRPe Systolic BP
Effect of PM2.5 on Mediatorsb 0.42 (0.16, 0.68) 0.02 (−0.21, 0.25) −0.04 (−0.21, 0.14) 0.02 (−0.05, 0.09) −0.84 (−2.09, 0.41)
Mediators’ effects on CCFMc −0.09 (−0.11, −0.06) −0.12 (−0.16, −0.08) −0.21 (−0.27, −0.15) 0.15 (0.00, 0.29) −0.01 (−0.02, −0.001)
Effect of PM2.5 on CCFM with mediators includedd −0.16 (−0.42, 0.10)* −0.13 (−0.40, 0.13) −0.11 (−0.37, 0.16) −0.16 (−0.48, 0.16) −0.21 (−0.47, 0.06)
a

Contains participants in Wave 1 and Wave 2 who completed CCFM and SPMSQ cognitive tests and had available mediator data; models include adjustment for race/ethnicity, gender, education (<H.S., H.S., College), age, season, smoking, region, median household income of census tract

b

Mediator test run on mediators in Wave 2, controlling for mediators in Wave 1, results per IQR increase in 1 year moving average PM2.5 from Wave 1

c

Test run between mediator in Wave 1 and CCFM outcome in Wave 2, controlling for SPMSQ results in Wave 1

d

Results per IQR increase in 1 year moving average PM2.5 in Wave 2, controlling for SPMSQ results in Wave 1

e

CRP values log transformed

*

p<0.05 for value of Sobel test