Table 2.

Univariate and multivariate logistic regression analysis of risk factors

Risk Factors	Overall Survival (OS)
	Univariate analysis		Multivariate analysis
	OR (95% CI)	P value	OR (95% CI)	P value
Gender
(Female or Male)	0.714 (0.457–1.115)	0.139	–	–
Age
(>  60 years or ≤ 60 years)	1.015 (0.992–1.038)	0.192	–	–
Tumor size (cm)
(>  5 or ≤ 5)	0.848 (0.538–1.337)	0.478	–	–
Depth of invasion	2.062 (0.745–5.705)	0.164	–	–
(T3–4 or T1–2)
Lymphonodus metastasis
(N2 or N0–1)	2.116 (1.316–3.403)	0.002**	0.544 (0.166–1.777)	0.313
AJCC stage
(III orI-II)	2.764 (1.641–4.657)	0.000**	4.199 (1.237–14.24)	0.021*
Pre-treatment LY
(>  1.535 × 109/L or ≤ 1.535 × 109/L)	1.474 (0.987–2.200)	0.058	–	–
Pre-treatment MO
(> 0.330 × 109/L or ≤ 0.330 × 109/L)	1.067 (0.722–1.576)	0.745	–	–
Pre-treatment NE
(>  3.325 × 109/L or ≤ 3.325 × 109/L)	1.585 (1.060–2.371)	0.025*	0.868 (0.522–1.444)	0.586
Pre-treatment EO
(> 0.090 × 109/L or ≤ 0.090 × 109/L)	0.924 (0.618–1.382)	0.702	–	–
Pre-treatment BA
(> 0.010 × 109/L or ≤ 0.010 × 109/L)	1.151(0.775–1.709)	0.486	–	–
Pre-treatment total WBC
(>  5.361 × 109/L or ≤ 5.361 × 109/L)	2.023 (1.329–3.081)	0.001**	1.751 (1.045–2.935)	0.033*
Post/pre-treatment LY ratio
(>  1 or ≤ 1)	0.839 (0.563–1.249)	0.387	–	–
Post/pre-treatment MO ratio
(>  1 or ≤ 1)	1.036 (0.703–1.527)	0.860	–	–
Post/pre-treatment NE ratio
(>  1 or ≤ 1)	0.871 (0.571–1.329)	0.521	–	–
Post/pre-treatment EO ratio
(>  1 or ≤ 1)	1.180 (0.796–1.748)	0.410	–	–
Post/pre-treatment BA ratio
(>  1 or ≤ 1)	1.006 (0.638–1.585)	0.980	–	–
Post/pre-treatment total WBC ratio
(>  1 or ≤ 1)	0.766 (0.508–1.154)	0.202	–	–

*P<0.05; **P<0.01