Table 2.
The clinicopathological characteristics stratified by the CONUT score
| Low CONUT group | High CONUT group | P value | |
|---|---|---|---|
| (n = 480) | (n = 217) | ||
| Age (years) | 0.070 | ||
| < 60 | 296 | 118 | |
| ≥ 60 | 184 | 99 | |
| Sex | 0.247 | ||
| Female | 172 | 68 | |
| Male | 308 | 149 | |
| Tumor size (cm) | 0.002 | ||
| < 5 | 261 | 91 | |
| ≥ 5 | 219 | 126 | |
| Tumor location | 0.062 | ||
| Lower third | 183 | 99 | |
| Upper/Middle third | 297 | 118 | |
| Histological grade | 0.053 | ||
| Well differentiated | 56 | 37 | |
| Poorly differentiated | 424 | 180 | |
| Lauren histotype | 0.403 | ||
| Intestinal | 103 | 59 | |
| Diffuse / Mixed | 221 | 107 | |
| LVI | 0.096 | ||
| Absent | 362 | 106 | |
| Present | 27 | 14 | |
| pT stage | 0.134 | ||
| pT1/2 | 45 | 13 | |
| pT3/4 | 435 | 204 | |
| pN stage | 0.010 | ||
| pN0/1 | 190 | 64 | |
| pN2/3 | 290 | 153 | |
| Dissected lymph nodes | 0.090 | ||
| ≤ 29 | 355 | 147 | |
| > 29 | 125 | 70 | |
| TNM stage | 0.324 | ||
| II | 139 | 55 | |
| III | 341 | 162 | |
| Operation type | 0.109 | ||
| Subtotal | 332 | 163 | |
| Total/extended | 148 | 54 | |
| Complications | 0.161 | ||
| No | 375 | 159 | |
| Yes | 105 | 58 | |
| Performance status | 0.527 | ||
| 0 | 119 | 49 | |
| 1/2 | 361 | 168 | |
| BMI (Kg/m2) | 0.009 | ||
| < 18.5 | 294 | 110 | |
| 18.5≤ | 186 | 107 | |
| PNI | < 0.001 | ||
| ≥ 45 | 480 | 137 | |
| < 45 | 0 | 80 | |
| Anemia | < 0.001 | ||
| No | 378 | 110 | |
| Yes | 102 | 107 | |
| CEA | 0.164 | ||
| Normal | 381 | 162 | |
| Elevated | 99 | 55 | |
| CA19–9 | 0.633 | ||
| Normal | 375 | 166 | |
| Elevated | 105 | 51 | |
| CA72–4 | 0.738 | ||
| Normal | 364 | 161 | |
| Elevated | 116 | 56 |
Abbreviations: CONUT controlling nutritional status, LVI lymphatic vessel infiltration, TNM tumor-node-metastasis staging, BMI body mass index, PNI prognostic nutritional index, CEA carcinoembryonic antigen, CA carbohydrate antigen