Table 2.
Numbers of voxels in different AAL2 areas with significantly different FC with amygdala voxels in patients with depression
| Areas | # Voxels | Peak MA value | MNI coordinates (Peak) | ||
|---|---|---|---|---|---|
| x | y | z | |||
| Frontal_Med_Orb_L, Frontal_Med_Orb_R, Rectus_L, Rectus_R, OFCmed_L, OFCmed_R, OFCant_L, OFCant_R, OFCpost_L, OFCpost_R, Olfactory_L, Olfactory_R | 634 | 101 | −30 | 27 | −18 |
| Frontal_Inf_Orb_2_L, Frontal_Inf_Orb_2_R, OFClat_L, OFClat_R | 131 | 62 | −24 | 12 | −21 |
| Hippocampus_R, ParaHippocampal_L, ParaHippocampal_R | 54 | 60 | 30 | −15 | −30 |
| Temporal_Pole_Sup_L, Temporal_Pole_Sup_R, Temporal_Pole_Mid_L, Temporal_Pole_Mid_R | 198 | 47 | 45 | 9 | −42 |
| Fusiform_L, Fusiform_R, Temporal_Sup_L, Temporal_Sup_R, Temporal_Mid_L, Temporal_Mid_R, Temporal_Inf_L, Temporal_Inf_R | 415 | 55 | 30 | −15 | −33 |
| Cingulate_Mid_L, Cingulate_Mid_R | 110 | 51 | 12 | 27 | −21 |
| Precentral_L, Precentral_R, Rolandic_Oper_L, Rolandic_Oper_R, Postcentral_L, Postcentral_R | 199 | 34 | −36 | 9 | −42 |
| Caudate_L, Caudate_R, Putamen_L, Putamen_R, Pallidum_L, Pallidum_R | 81 | 23 | −39 | 0 | −42 |
| Frontal_Sup_2_L, Frontal_Sup_2_R, Frontal_Mid_2_L, Frontal_Mid_2_R, Frontal_Inf_Tri_L | 380 | 45 | 33 | −18 | −30 |
| Insula_L, Insula_R | 68 | 82 | −27 | 21 | −21 |
| Cuneus_R, L ingual_L, Lingual_R, Occipital_Sup_L, Occipital_Sup_R, Occipital_Mid_L, Occipital_Mid_R, Occipital_Inf_L, Occipital_Inf_R | 651 | 77 | 33 | −9 | −12 |
| Frontal_Sup_2_L, Frontal_Sup_2_R | 221 | 45 | 33 | −18 | −30 |
| Amygdala_L, Amygdala_R | 149 | 4267 | −27 | −3 | −21 |
| Frontal_Inf_Oper_L | 41 | 24 | −36 | 12 | 15 |
| Frontal_Sup_Medial_L | 26 | 15 | −6 | 63 | 0 |
| Calcarine_R | 41 | 33 | 15 | −93 | 12 |
| Frontal_Sup_Medial_L, Frontal_Sup_Medial_R | 58 | 39 | −12 | 60 | 27 |
| Supp_Motor_Area_L, Supp_Motor_Area_R | 86 | 52 | −12 | 0 | 69 |
The peak MA value shown is the number of links between the peak voxel in the brain regions listed under ‘Areas’ and the amygdala voxels, where these links are significantly different FDR corrected at P < 0.05. The MNI coordinates are the peak of the cluster in the brain regions listed under ‘Areas’. In all cases in this table, the FC links are weaker in the depressed group; thus these MA values show the number of decreased FC links in the depression group. There were a total of 97 740 links between the voxels of amygdala and other brain areas which showed a significant difference between controls and patients with depression (FDR correction, P < 0.05).