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. 2018 Mar 16;109(5):604–609. doi: 10.1093/jhered/esy014

Figure 1.

Figure 1.

Allelic variation in the GRC region influences the microbiome of BgGUA. (A) OTU composition of the microbiome in homozygous inbred lines (isolated from each other for >3 years; n = 12 RR, 7 S1S1, and 11 S2S2 lines) of BgGUA, as depicted with NMDS of OTUs generated. Overall community composition of S1S1 is significantly different (PERMANOVA Bray–Curtis, P = 0.03) from the other 2 genotypes, although all 3 genotypes show similarly high variability and did not have differing diversity (H). The relative abundance of Micavibrio aeruginosavorus ARL-13 is significantly different in RR lines (uncorrected P = 1.8e-04; α = 0.05/223 = 2.2e-04). (B) OTU composition of the microbiome in outbred BgGUA (2 tanks separated for >1 year) (tank 1: n = 5 S2S2, 7 S1S2, 4 S1R, 14 RR, 19 S2R; tank 2: n = 15 S2S2, 3 S1S2, 6 S1R, 10 RR, 12 S2R), as depicted with NMDS. Allelic variation in the GRC region has no significant influence on the OTU composition or abundance but a significant difference in diversity (H, P = 0.04). All genotypes show similarly high variability.