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Effect of injected mass of 11C-FLB457 on the binding potential (BPND) in dlPFC. Graph shows original 11C-FLB457 BPND values of the dlPFC (circles) or corrected for age (triangles) plotted against every subject’s injected mass gathered under control condition in this study (open symbols) or control conditions of an unpublished study (filled symbols), and the non-linear fitted curve (black line). The estimated ED50 is 0.124 μg/kg.
