Skip to main content
. 2018 Jun 27;34(13):i447–i456. doi: 10.1093/bioinformatics/bty289

Table 2.

Comparison of the average BEDROC scores calculated with various α, for GeneHouds and Endeavour

Methods Averaged BEDROC score

α α=228.5 α=160.9 α=32.2 α=16.1 α=5.3
Early enrichment focus TOP 100 TOP 1% TOP 5% TOP 10% TOP 30%
GeneHound_25LatDims 0.358 ± 0.057 0.396 ± 0.06 0.595 ± 0.056 0.686 ± 0.045 0.818 ± 0.023
GeneHound_30LatDims 0.36 ± 0.016 0.40 ± 0.017 0.608 ± 0.028 0.70 ± 0.029 0.829 ± 0.019
GeneHound_40LatDims 0.383 ± 0.023 0.421 ± 0.024 0.614 ± 0.027 0.699 ± 0.026 0.824 ± 0.017
GeneHound_GeoAgg 0.418 ± 0.031 0.458 ± 0.031 0.651 ± 0.031 0.733 ± 0.029 0.85 ± 0.018
Endeavour 0.387 ± 0.031 0.422 ± 0.030 0.609 ± 0.029 0.694 ± 0.029 0.817 ± 0.021

Notes: The confidence intervals are reported over folds. α tunes the early enrichment. For example, in our study when α=228.5, 80% of BEDROC score is given to the top 100 ranked genes. The best performance for each α is shown in boldface. All models are benchmarked on OMIM2.

The maximum BEDROC scores at different early enrichment focuses are highlighted in bold.