Table 2.
Gene orthologs (GO) significantly modified by green tea polyphenols.
| GOa | Category | Function |
|---|---|---|
| 3 months treatment | ||
| Decreased | ||
| ENOG4105D70 | L | Integrase catalytic subunit |
| ENOG4105F5W | L | ATP-binding protein |
| ENOG4105EGG | V | ABC transporter |
| ENOG4105EXR | S | Unknown |
| ENOG4105CK0 | M | Membrane bound o-acyl transferase |
| ENOG4108SJI | M | Hydrolase, family 25 |
| Increased | ||
| K01869 | J | Leucyl-tRNA synthetase |
| ENOG4105WBW | S | Relaxase mobilization nuclease domain protein |
| ENOG4105EUN | L | Transposase |
| ENOG4105CCY | C | NADH flavin oxidoreductase, NADH oxidase |
| 6 months treatment | ||
| Decreased | ||
| ENOG4105D2F | G | Ig domain protein, group 2 domain protein |
| ENOG4105CDX | S | Unknown |
| ENOG4105XN2 | K | DNA-binding helix-turn-helix protein |
| ENOG4105C19 | V | ABC transporter |
| ENOG4108KGH | K | Transcriptional regulator |
| ENOG410667J | S | Hydrolase |
| ENOG4108SJI | M | Hydrolase, family 25 |
| ENOG4108VXD | M | Carboxypeptidase |
| ENOG4108UUM | L | Single-stranded DNA-binding protein |
| ENOG4105EF7 | K | Transcriptional regulator |
| ENOG4105DAV | K | RNA polymerase sigma factor RpoD |
| ENOG4108M4B | M | Domain protein |
| ENOG4105DZ1 | M | Carboxypeptidase |
| ENOG4105C5C | M | N-acetylmuramoyl-L-alanine amidase |
| Increased | ||
| ENOG4105F42 | S | AAA-ATPase |
| ENOG4105K8S | S | Unknown |
| ENOG4108J2R | C | Molybdopterin oxidoreductase |
| ENOG4105FAP | L | Transposase |
| ENOG4107WWN | L | Transposase |
| ENOG41063CS | L | Replication Protein |
| ENOG4105FGY | P | TonB-dependent receptor, Plug Domain |
| K01869 | J | Leucyl-tRNA synthetase |
| ENOG4105DAB | C | Fumarate reductase/succinate dehydrogenase, Flavoprotein |
| domain protein | ||
| ENOG4105CGS | G | Alpha-glucosidase |
| ENOG4105D3S | C | 4Fe-4S ferredoxin, iron-sulfur binding domain protein |
| ENOG4107VV4 | S | Virulence-associated protein e |
| ENOG4105X7U | K | Transcriptional regulator, ARAC family |
| ENOG4106DHI | S | Cleaved adhesin domain protein |
| ENOG4105CCY | C | NADH flavin oxidoreductase, NADH oxidase |
| ENOG4105WBW | S | Relaxase mobilization nuclease domain protein |
a
The gene ortholog ID, category, and function were assigned based on eggNOG v4.5 database except for K01869, which was assigned based on KEGG database.