Table 4.

Screening data for neutral amides 72–86.

Ar	Cmpd	R1 & R2	CC50 (μM)
			HT29	PC3	MDA-MB-231
	72	R1 = H, R2 = benzyl	1.52±0.39	16.36±8.55	3.61±1.87
	73	R1 = H, R2 = furan-2-ylmethyl	2.08±0.82	12.98±6.83	3.40±1.07
	74	R1 = H, R2 = thiophen-2-ylmethyl	2.16±0.71	11.03±5.95	5.66±2.69
	75	R1 = H, R2 = -CH2CH2CH(CH3)2	>50.00	>50.00	>50.00
	76	R1 = H, R2 = D-Alanine methyl ester	16.22±2.61	44.18±7.38	31.99±2.33
	77	R1 = H, R2 = L-Alanine methyl ester	23.92±1.92	>50.00	38.86±6.04
	78	R1 = H, R2 = L-Histidine methyl ester	23.01±3.09	>50.00	>50.00
	79	R1 = H, R2 = benzyl	0.50±0.23	2.64±1.19	0.78±0.32
	80	R1 = H, R2 = furan-2-ylmethyl	1.00±0.50	>50.00	2.73±1.21
	81	R1 = H, R2 = -CH2CH2CH(CH3)2	17.65±1.11	20.23±2.29	27.72±3.37
	82	R1 = H, R2 = -CH2CH2CH(CH3)2	5.24±1.18	8.20±1.92	8.73±1.97
	83	R1 = H, R2 = benzyl	23.56±2.04	>50.00	19.63±2.98
	84	R1 = H, R2 = furan-2-ylmethyl	5.48±1.70	26.44±15.80	6.70±2.23
	85	R1 = H, R2 = -CH2CH2CH(CH3)2	>50.00	>50.00	24.20±5.35
	86	R1 = H, R2 = benzyl	2.14±0.46	5.71±1.75	3.68±1.10