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. Author manuscript; available in PMC: 2018 Nov 21.
Published in final edited form as: Nat Immunol. 2018 May 21;19(7):776–786. doi: 10.1038/s41590-018-0121-3

Figure 3. Examples of baseline molecules which associate differentially to cytokine responses.

Figure 3

IL-18BP, a circulating inhibitor of IL-18, displays negative Spearman correlations with general cytokine production capacity of lymphocytes after correcting for age and gender effects (n=489). The metabolite acetate positively correlates with stimulated cytokine production in response to influenza and displays a mostly positive effect on lymphocyte-derived cytokines after correcting for age and gender effects (n=377). Each sample represents an individual.