Selection bias
|
Random sequence generation |
Participants were randomly assigned by means of a draw |
Low risk of bias |
Allocation concealment |
Medications were stored in opaque-coloured bottles identified only by the respective code of each participant |
Low risk of bias |
Performance bias
|
Blinding of participants |
Participants were masked from medications types |
Low risk of bias |
Blinding of personnel |
Both periodontists involved in the treatment and clinical examination were masked from the identity of participants |
Low risk of bias |
Detection bias
|
Blinding of outcome assessor |
Blinding was ensured |
Low risk of bias |
Attrition bias
|
Incomplete outcome data |
There was no drop out of participants |
Low risk of bias |
Reporting bias
|
Selective reporting |
The article includes all expected outcomes, including those that were pre-specified |
Low risk of bias |