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. 2018 Jun 6;243(10):864–875. doi: 10.1177/1535370218782139

Figure 3.

Figure 3.

Measures of disease activity. Scoring system adapted from Murthy et al. Dig Dis Sci 1993 and Singh et al. Immunity 2014. n = 10 to 12 per group at the start of the study; n declined over time as shown in the survival curve. Mean ± SEM. Points without a common letter differ on the given day; P < 0.05. (a) Average body weight. (b) Average fecal score. Scoring system: 0 = Normal stool, 1 = Soft but formed pellet, 2 = Very soft pellet, 3 = Diarrhea (no pellet), 4 = Dysenteric diarrhea (blood in diarrhea). (c) Average rectal bleeding score. Scoring system: 0 = No visible blood, 2: presence of visible blood in stool (red/dark pellet), 4: gross macroscopic bleeding (blood around anus). (d) Disease activity index. Average of body weight loss, fecal consistency, and rectal bleeding scores.