Figure 3.

MiR-145 expression was down-regulated during hASCs osteogenesis. (a) Heat map revealed the miR-145 was lower expressed after hASCs osteogenic differentiation. (b) Volcano plot showed the miR-145 was lower expressed after hASCs osteogenic differentiation. (c) MiR-145 expression was downregulated gradually along with osteoinductive differentiation. (d) There is a significantly negative correlation between miR-145 and FoxO1 expression. *P < 0.05, **P < 0.01 compared with day 0. (A color version of this figure is available in the online journal.)