Table 2. Method discordances and the MYCOTB plate MICs.
Discordance | Frequency | MYCOTB plate MIC |
---|---|---|
Rifampicin (40mg/ml) | ||
LJr, MB7H10r, MYCOTBs | 3 | 1–2 |
LJs, MB7H10r, MYCOTBs | 4 | 0.12–1 |
LJr, MB7H10s, MYCOTBs | 4 | 0.12–1β |
LJs, MB7H10r, MYCOTBr | 7 | 4 - >16* |
LJr, MB7H10s, MYCOTBr | 0 | |
LJs, MB7H10s, MYCOTBr | 0 | |
Isoniazid (1.0mg/ml) | ||
LJr, MB7H10r, MYCOTBs | 3 | 2 |
LJs, MB7H10r, MYCOTBs | 3 | 2 |
LJr, MB7H10s, MYCOTBs | 11 | 0.03–1ƚ |
LJs, MB7H10r, MYCOTBr | 7 | >4 |
LJr, MB7H10s, MYCOTBr | 0 | |
LJs, MB7H10s, MYCOTBr | 0 | |
Streptomycin | ||
LJr, MB7H10r, MYCOTBs | 0 | |
LJs, MB7H10r, MYCOTBs | 0 | |
LJr, MB7H10s, MYCOTBs | 25 | 0.25–16 |
LJs, MB7H10r, MYCOTBr | 2 | 32, > 32 |
LJr, MB7H10s, MYCOTBr | 1 | >32 |
LJs, MB7H10s, MYCOTBr | 0 | |
Ethambutol | ||
LJr, MB7H10r, MYCOTBs | 0 | |
LJs, MB7H10r, MYCOTBs | 0 | |
LJr, MB7H10s, MYCOTBs | 17 | 0.5–16# |
LJs, MB7H10r, MYCOTBr | 0 | |
LJr, MB7H10s, MYCOTBr | 0 | |
LJs, MB7H10s, MYCOTBr | 0 |
r = resistant, s = Susceptible, LJ = Lowenstein Jensen, MB = Middlebrook, MYCOTB = sensititre MYCOTB plate, MIC = minimum inhibitory concentration βMIC 1 (n = 1), 0.12 (n = 3)
*MIC 4 (n = 1), 16 (n = 1) and >16 (n = 5)
ƚMIC 4 (n = 1), 2 (n = 1) below 1 (n = 10), #MIC 16 (n = 1), 8 (n = 6) >8 (n = 10)