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. 2018 Jun 28;13(6):e0199638. doi: 10.1371/journal.pone.0199638

Table 2. Method discordances and the MYCOTB plate MICs.

Discordance Frequency MYCOTB plate MIC
Rifampicin (40mg/ml)
LJr, MB7H10r, MYCOTBs 3 1–2
LJs, MB7H10r, MYCOTBs 4 0.12–1
LJr, MB7H10s, MYCOTBs 4 0.12–1β
LJs, MB7H10r, MYCOTBr 7 4 - >16*
LJr, MB7H10s, MYCOTBr 0
LJs, MB7H10s, MYCOTBr 0
Isoniazid (1.0mg/ml)
LJr, MB7H10r, MYCOTBs 3 2
LJs, MB7H10r, MYCOTBs 3 2
LJr, MB7H10s, MYCOTBs 11 0.03–1ƚ
LJs, MB7H10r, MYCOTBr 7 >4
LJr, MB7H10s, MYCOTBr 0
LJs, MB7H10s, MYCOTBr 0
Streptomycin
LJr, MB7H10r, MYCOTBs 0
LJs, MB7H10r, MYCOTBs 0
LJr, MB7H10s, MYCOTBs 25 0.25–16
LJs, MB7H10r, MYCOTBr 2 32, > 32
LJr, MB7H10s, MYCOTBr 1 >32
LJs, MB7H10s, MYCOTBr 0
Ethambutol
LJr, MB7H10r, MYCOTBs 0
LJs, MB7H10r, MYCOTBs 0
LJr, MB7H10s, MYCOTBs 17 0.5–16#
LJs, MB7H10r, MYCOTBr 0
LJr, MB7H10s, MYCOTBr 0
LJs, MB7H10s, MYCOTBr 0

r = resistant, s = Susceptible, LJ = Lowenstein Jensen, MB = Middlebrook, MYCOTB = sensititre MYCOTB plate, MIC = minimum inhibitory concentration βMIC 1 (n = 1), 0.12 (n = 3)

*MIC 4 (n = 1), 16 (n = 1) and >16 (n = 5)

ƚMIC 4 (n = 1), 2 (n = 1) below 1 (n = 10), #MIC 16 (n = 1), 8 (n = 6) >8 (n = 10)