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. 2001 Oct 1;29(19):4025–4034. doi: 10.1093/nar/29.19.4025

Figure 1.

Figure 1

Formation and reactions of N1,O6-ethanoguanine. Intramolecular cyclization of the initial chloroethylnitrosourea adduct (a) generates the reactive ethano intermediate which can crosslink DNA (b), be ‘repaired’ by AGT (c) or react with water (d).