Table 1. Comparsion of patients according to AST level.
| Variable | All, N = 1716 | AST<37, N = 132 | 37<AST≤74, N = 501 | 74<AST≤148 IU/L, N = 737 | AST>148 IU/L, N = 346 | P |
|---|---|---|---|---|---|---|
| Age (years) | 52.5±11.6 | 46.7±12 | 50.1±12.2 | 53.9±10.7 | 55.3±10.7 | <0.001 |
| Male gender, N (%) | 913 (53.2%) | 65 (49.2%) | 294 (58.7%) | 383 (52.0%) | 171 (49.4%) | 0.025 |
| Genotype, N (%) | 0.099 | |||||
| 1 | 728 (46.7%) | 47 (40.2%) | 230 (49.8%) | 322 (48.6%) | 129 (40.6%) | |
| 2 | 756 (48.5%) | 59 (50.4%) | 211 (45.7%) | 312 (47.1%) | 174 (54.7%) | |
| Mixed | 50 (3.2%) | 8 (6.8%) | 13 (2.8%) | 19 (2.9%) | 10 (3.1%) | |
| Others | 26 (1.6%) | 3 (2.6%) | 8 (1.7%) | 10 (1.5%) | 5 (1.6%) | |
| Missing data | 156 (9.1%) | 15 (11.4%) | 39 (7.8%) | 74 (10.0%) | 28 (8.1%) | |
| BMI (kg/m2) | 24.6±3.5 | 23.8±3.4 | 24.7±3.4 | 24.7±3.6 | 24.7±3.5 | 0.09 |
| Missing data | 181 (10.6%) | 22 (16.7%) | 47 (9.4%) | 70 (9.5%) | 42 (12.1%) | |
| Necroinflammation score | 7.3±2.3 | 5.1±2.0 | 6.6±2.2 | 7.7±2.1 | 8.2±2.3 | <0.001 |
| Fibrosis | <0.001 | |||||
| 0 | 325 (18.9%) | 77 (58.3%) | 128 (25.5%) | 73 (9.9%) | 47 (13.6%) | |
| 1 | 483 (28.2%) | 23 (17.4%) | 178 (35.5%) | 209 (28.4%) | 73 (21.1%) | |
| 2 | 163 (9.5%) | 9 (6.8%) | 48 (9.6%) | 78 (10.6%) | 28 (8.1%) | |
| 3 | 309 (18.0%) | 17 (12.9%) | 65 (13%) | 150 (20.4%) | 77 (22.3%) | |
| 4 | 436 (25.4%) | 6 (4.5%) | 82 (16.4%) | 227 (30.8%) | 121 (35.0%) | |
| HCV RNA >600,000 IU/ml, N (%) | 262 (27.3%) | 37 (38.9%) | 92 (31.2%) | 81 (21.2%) | 52 (27.8%) | 0.001 |
| Only qualitative HCV RNA was available, N (%) | 756 (44.1%) | 37 (28%) | 206 (41.1%) | 354 (48.0%) | 159 (46.0%) | |
| ALT (IU/L) | 134 (93–205.5) | 44 (32–57) | 92 (75–111) | 152 (120–195) | 273.5 (209–366) | <0.001 |
| Platelet (109/L) <150 | 680 (39.6%) | 24 (18.2%) | 152 (30.3%) | 341 (46.3%) | 163 (47.1%) | <0.001 |
| Bilirubin (mg/dL) | 0.9±0.6 | 0.9±0.5 | 0.9±0.5 | 0.9±0.6 | 1.0±0.8 | 0.75 |
| Albumin (mg/dL) | 3.9±0.6 | 4.0±0.4 | 4.2±0.4 | 3.9±0.6 | 3.7±0.6 | <0.001 |
| INR | 1.0±0.1 | 1.1±0.1 | 1.0±0.1 | 1.0±0.1 | 1.1±0.1 | 0.04 |
Data were expressed as mean ± SD or median (interquantile). BMI, body mass index; AST, Aspartate Aminotransferase; ALT, Alanine Aminotransferase; INR, international normalized ratio