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. 2018 Jun 28;13(6):e0199827. doi: 10.1371/journal.pone.0199827

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© 2018 Silakit et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) The expression of miR-210 was determined in CCA tumor tissues (n = 38) compared to adjacent non-tumorous tissues (n = 30) or normal bile duct (NBD) (n = 5). Data were normalized with U6 snRNA. A Mann–Whitney U-test showed that miR-210 was significantly increased in tumor tissues compared with adjacent non-tumorous tissues (P < 0.001) and normal bile ducts (NBD) (P < 0.001). (B) Kaplan-Meier curves of overall survival in CCA patients showed that patients with high miR-210 expression levels (dense line; n = 16) had significantly lower survival rates than those with low miR-210 expression levels (dotted line; n = 22; P = 0.009).