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. 2018 Jun 28;13(6):e0199827. doi: 10.1371/journal.pone.0199827

Table 2. IC50 value and sensitivity index in stable CCA cell lines to gemcitabine.

Conditions IC50 value of gemcitabine (μM)
Normoxia SI P-value Hypoxia SI P-value
KKU-213-pMSCV 0.10±0.02 0.42±0.21
KKU-213-pMSCV-miR210 0.09±0.01 1.12 0.257 3.58±1.23 0.12 0.013*
KKU-100-control vector 0.46±0.05 0.81±0.07
KKU-100-miR210 sponge 0.07±0.01 7.03 <0.001* 0.09±0.01 9.26 0.003*

SI, sensitivity index.

*P-value less than 0.05 was considered statistically significant.