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. 2018 Jun 28;13(6):e0198777. doi: 10.1371/journal.pone.0198777

Table 2. Characteristics of participating hospitals and respiratory unit resources, by COPD patients with/without serum AAT levels tested.

Centers All patients
(n = 4,408)
COPD patients with serum AAT levels tested
(n = 995)
COPD patients without serum AAT levels tested
(n = 3,413)
OR (95%CI) p
Large hospital, (%) 62.9 67.4 61.6 1.41 (0.79–2.50) 0.240
University hospital, (%) 88 88.5 87.9 1.02 (0.44–2.32) 0.962
Beds per center ≥500, (%) 71.9 74.2 71.2 1.18 (0.64–2.17) 0.581
Respiratory ward not available, (%) 11.5 8.1 12.5 Reference
Respiratory ward<20 beds 13.4 12.9 13.5 1.46 (0.49–4.31) 0.485
Respiratory ward≥20 beds 75 78.9 73.8 1.58 (0.68–3.67) 0.278
Number of pulmonology staff members ≥5, (%) 78.9 80.2 78.5 0.80 (0.35–1.86) 0.620
Pulmonology residents present, (%) 74.1 75.2 73.8 1.01 (0.53–1.91) 0.963
Number of annual outpatient respiratory visits ≥ 10,000, (%) 88.8 93.3 87.4 2.18 (0.99–4.79) 0.05
≥ 15 minutes of follow-up at general outpatient respiratory visit, (%) 41.9 42.9 417 1.16 (0.65–2.06) 0.618
AATD genotyping availability, (%) 74.1 77.3 73.2 1.41 (0.75–2.65) 0.284
Specialized COPD outpatient clinic available, (%) 52.5 61.4 50 1.91 (1.10–3.32) 0.021
Outpatient respiratory nursing clinic availability, (%) 45.9 50.4 44.5 1.32 (0.75–2.33) 0.333
Inhalation technique educational program available, (%) 29.9 33.8 28.8 1.23 (0.67–2.28) 0.494

The necessary criteria to consider a hospital large are: the number of beds per center ≥500, the number of inpatient respiratory beds ≥20, the number of pulmonology staff members ≥5, and the number of annual outpatient respiratory visits ≥10,000.